Endocrine Abstracts

Hashimoto disease, a chronic autoimmune lymphocytic thyroiditis, is the most common cause of hypothyroidism with a prevalence of 10–12% in the general population. Literature data suggests that persistently high levels of oxidative are considered as relevant risk factor in the occurrence and development of autoimmune diseases, including Hashimoto. The DNA and RNA are particularly valuable to the oxidative damage, and guanine is the most prone base to oxidation. Thus, the D...

Recently, 59 percent of European adults was diagnosed with obesity or overweight according to the 2022 Regional Obesity Report presented by the World Health Organization (WHO). Thus, insight into factors implicated in overweight and obesity may have important therapeutic implications. Interestingly, increased cortisol secretion and psychosocial stress have been demonstrated to be related with body weight-dependent insulin resistance and beta cells failure. Thus, the study was ...